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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MLXIPL
All Species:
11.82
Human Site:
S614
Identified Species:
20
UniProt:
Q9NP71
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NP71
NP_116569.1
852
93073
S614
S
G
S
E
R
R
L
S
G
D
L
S
S
M
P
Chimpanzee
Pan troglodytes
XP_509441
819
90122
S584
P
S
R
D
C
P
N
S
G
Q
A
S
P
C
A
Rhesus Macaque
Macaca mulatta
XP_001115131
390
43669
V177
W
K
R
R
I
E
V
V
M
R
E
Y
H
K
W
Dog
Lupus familis
XP_546925
857
93734
S619
S
G
G
K
R
R
L
S
G
E
L
S
S
M
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q99MZ3
864
94857
S626
S
G
S
E
R
R
L
S
G
D
L
N
S
I
Q
Rat
Rattus norvegicus
Q6AXT8
471
49872
G258
L
P
P
P
P
P
G
G
L
P
L
P
P
M
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001104311
895
97370
K658
V
C
G
S
D
W
P
K
P
G
Q
V
S
P
G
Frog
Xenopus laevis
NP_001084764
548
60887
T335
P
C
S
P
V
S
Q
T
S
A
L
P
S
S
T
Zebra Danio
Brachydanio rerio
XP_001338503
817
90800
G589
V
Q
S
A
T
R
D
G
R
I
S
G
Q
G
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_724328
836
92381
V593
I
G
L
A
T
A
N
V
G
S
N
S
L
S
L
Honey Bee
Apis mellifera
XP_394429
1014
115124
G775
S
N
A
H
S
P
Q
G
L
N
L
S
P
L
H
Nematode Worm
Caenorhab. elegans
P41846
1009
112841
F676
G
S
P
T
Y
Q
A
F
A
A
S
V
T
T
K
Sea Urchin
Strong. purpuratus
XP_788672
1338
148936
S1076
T
P
I
K
M
L
S
S
E
P
P
K
T
Q
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LVN1
1266
139556
K846
L
K
P
Y
H
W
L
K
L
T
R
A
V
N
G
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
41.6
42.9
87.7
N.A.
81.4
20.8
N.A.
N.A.
51.4
30.9
39.4
N.A.
20
29.5
25.5
21.1
Protein Similarity:
100
55.4
43.9
91.4
N.A.
85.7
29.3
N.A.
N.A.
60.7
41.6
53.5
N.A.
36.5
44.9
41.3
33.5
P-Site Identity:
100
20
0
73.3
N.A.
80
20
N.A.
N.A.
6.6
20
13.3
N.A.
20
20
0
6.6
P-Site Similarity:
100
26.6
6.6
86.6
N.A.
93.3
20
N.A.
N.A.
6.6
26.6
13.3
N.A.
20
40
13.3
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.5
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
34
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
15
0
8
8
0
8
15
8
8
0
0
8
% A
% Cys:
0
15
0
0
8
0
0
0
0
0
0
0
0
8
0
% C
% Asp:
0
0
0
8
8
0
8
0
0
15
0
0
0
0
0
% D
% Glu:
0
0
0
15
0
8
0
0
8
8
8
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% F
% Gly:
8
29
15
0
0
0
8
22
36
8
0
8
0
8
15
% G
% His:
0
0
0
8
8
0
0
0
0
0
0
0
8
0
8
% H
% Ile:
8
0
8
0
8
0
0
0
0
8
0
0
0
8
0
% I
% Lys:
0
15
0
15
0
0
0
15
0
0
0
8
0
8
8
% K
% Leu:
15
0
8
0
0
8
29
0
22
0
43
0
8
8
8
% L
% Met:
0
0
0
0
8
0
0
0
8
0
0
0
0
22
0
% M
% Asn:
0
8
0
0
0
0
15
0
0
8
8
8
0
8
0
% N
% Pro:
15
15
22
15
8
22
8
0
8
15
8
15
22
8
15
% P
% Gln:
0
8
0
0
0
8
15
0
0
8
8
0
8
8
15
% Q
% Arg:
0
0
15
8
22
29
0
0
8
8
8
0
0
0
0
% R
% Ser:
29
15
29
8
8
8
8
36
8
8
15
36
36
15
8
% S
% Thr:
8
0
0
8
15
0
0
8
0
8
0
0
15
8
15
% T
% Val:
15
0
0
0
8
0
8
15
0
0
0
15
8
0
0
% V
% Trp:
8
0
0
0
0
15
0
0
0
0
0
0
0
0
8
% W
% Tyr:
0
0
0
8
8
0
0
0
0
0
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _